SYNOPSIS

mia-3drigidreg -i <in> -r <ref> -o <out> [options]

DESCRIPTION

mia-3drigidreg This program implements the registration of two gray scale 3D images. The transformation is not penalized, therefore, one should only use translation, rigid, or affine transformations as target and run mia-3dnonrigidreg of nonrigid registration is to be achieved.

OPTIONS

File I/O

-i --in=(input,required)

test image For supported file types see PLUGINS:3dimage/io

-r --ref=(input,required)

reference image For supported file types see PLUGINS:3dimage/io

-o --out=(output,required)

registered output image For supported file types see PLUGINS:3dimage/io

-t --trans=(output)

transformation output file name For supported file types see PLUGINS:3dtransform/io

-c --cost=ssd

cost function For supported plugins see PLUGINS:3dimage/cost

-l --levels=3

multigrid levels

-O --optimizer=gsl:opt=simplex,step=1.0

Optimizer used for minimization For supported plugins see PLUGINS:minimizer/singlecost

-f --transForm=rigid

transformation type For supported plugins see PLUGINS:3dimage/transform

Help & Info

-V --verbose=warning

verbosity of output, print messages of given level and higher priorities. Supported priorities starting at lowest level are:

info \(hy Low level messages

trace \(hy Function call trace

fail \(hy Report test failures

warning \(hy Warnings

error \(hy Report errors

debug \(hy Debug output

message \(hy Normal messages

fatal \(hy Report only fatal errors

--copyright

print copyright information

-h --help

print this help

-? --usage

print a short help

--version

print the version number and exit

Processing

--threads=-1

Maxiumum number of threads to use for processing,This number should be lower or equal to the number of logical processor cores in the machine. (-1: automatic estimation).

PLUGINS: 1d/splinebc

mirror

Spline interpolation boundary conditions that mirror on the boundary

(no parameters)

repeat

Spline interpolation boundary conditions that repeats the value at the boundary

(no parameters)

zero

Spline interpolation boundary conditions that assumes zero for values outside

(no parameters)

PLUGINS: 1d/splinekernel

bspline

B-spline kernel creation , supported parameters are:

d = 3 (int)

Spline degree. in [0, 5]

omoms

OMoms-spline kernel creation, supported parameters are:

d = 3 (int)

Spline degree. in [3, 3]

PLUGINS: 3dimage/cost

lncc

local normalized cross correlation with masking support., supported parameters are:

w = 5 (uint)

half width of the window used for evaluating the localized cross correlation. in [1, 256]

mi

Spline parzen based mutual information., supported parameters are:

cut = 0 (float)

Percentage of pixels to cut at high and low intensities to remove outliers. in [0, 40]

mbins = 64 (uint)

Number of histogram bins used for the moving image. in [1, 256]

mkernel = [bspline:d=3] (factory)

Spline kernel for moving image parzen hinstogram. For supported plug-ins see PLUGINS:1d/splinekernel

rbins = 64 (uint)

Number of histogram bins used for the reference image. in [1, 256]

rkernel = [bspline:d=0] (factory)

Spline kernel for reference image parzen hinstogram. For supported plug-ins see PLUGINS:1d/splinekernel

ncc

normalized cross correlation.

(no parameters)

ngf

This function evaluates the image similarity based on normalized gradient fields. Given normalized gradient fields $ _S$ of the src image and $ _R$ of the ref image various evaluators are implemented., supported parameters are:

eval = ds (dict)

plugin subtype (sq, ds,dot,cross). Supported values are:

ds \(hy square of scaled difference

dot \(hy scalar product kernel

cross \(hy cross product kernel

ssd

3D image cost: sum of squared differences, supported parameters are:

autothresh = 0 (float)

Use automatic masking of the moving image by only takeing intensity values into accound that are larger than the given threshold. in [0, 1000]

norm = 0 (bool)

Set whether the metric should be normalized by the number of image pixels.

ssd-automask

3D image cost: sum of squared differences, with automasking based on given thresholds, supported parameters are:

rthresh = 0 (double)

Threshold intensity value for reference image. in [-1.79769e+308, 1.79769e+308]

sthresh = 0 (double)

Threshold intensity value for source image. in [-1.79769e+308, 1.79769e+308]

PLUGINS: 3dimage/io

analyze

Analyze 7.5 image

Recognized file extensions: .HDR, .hdr

Supported element types:

unsigned 8 bit, signed 16 bit, signed 32 bit, floating point 32 bit, floating point 64 bit

datapool

Virtual IO to and from the internal data pool

Recognized file extensions: .@

dicom

Dicom image series as 3D

Recognized file extensions: .DCM, .dcm

Supported element types:

signed 16 bit, unsigned 16 bit

hdf5

HDF5 3D image IO

Recognized file extensions: .H5, .h5

Supported element types:

binary data, signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

inria

INRIA image

Recognized file extensions: .INR, .inr

Supported element types:

signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

mhd

MetaIO 3D image IO using the VTK implementation (experimental).

Recognized file extensions: .MHA, .MHD, .mha, .mhd

Supported element types:

signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

nifti

NIFTI-1 3D image IO

Recognized file extensions: .NII, .nii

Supported element types:

signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

vff

VFF Sun raster format

Recognized file extensions: .VFF, .vff

Supported element types:

unsigned 8 bit, signed 16 bit

vista

Vista 3D

Recognized file extensions: .V, .VISTA, .v, .vista

Supported element types:

binary data, signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

vti

3D image VTK-XML in- and output (experimental).

Recognized file extensions: .VTI, .vti

Supported element types:

signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

vtk

3D VTK image legacy in- and output (experimental).

Recognized file extensions: .VTK, .VTKIMAGE, .vtk, .vtkimage

Supported element types:

binary data, signed 8 bit, unsigned 8 bit, signed 16 bit, unsigned 16 bit, signed 32 bit, unsigned 32 bit, floating point 32 bit, floating point 64 bit

PLUGINS: 3dimage/transform

affine

Affine transformation (12 degrees of freedom), supported parameters are:

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

axisrot

Restricted rotation transformation (1 degrees of freedom). The transformation is restricted to the rotation around the given axis about the given rotation center, supported parameters are:

axis = (required, 3dfvector)

rotation axis.

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

origin = (required, 3dfvector)

center of the transformation.

raffine

Restricted affine transformation (3 degrees of freedom). The transformation is restricted to the rotation around the given axis and shearing along the two axis perpendicular to the given one, supported parameters are:

axis = (required, 3dfvector)

rotation axis.

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

origin = (required, 3dfvector)

center of the transformation.

rigid

Rigid transformation, i.e. rotation and translation (six degrees of freedom)., supported parameters are:

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

origin = [[0,0,0]] (streamable)

Relative rotation center, i.e. <0.5,0.5,0.5> corresponds to the center of the volume.

rotation

Rotation transformation (three degrees of freedom)., supported parameters are:

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

origin = [[0,0,0]] (streamable)

Relative rotation center, i.e. <0.5,0.5,0.5> corresponds to the center of the volume.

rotbend

Restricted transformation (4 degrees of freedom). The transformation is restricted to the rotation around the x and y axis and a bending along the x axis, independedn in each direction, with the bending increasing with the squared distance from the rotation axis., supported parameters are:

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

origin = (required, 3dfvector)

center of the transformation.

spline

Free-form transformation that can be described by a set of B-spline coefficients and an underlying B-spline kernel., supported parameters are:

anisorate = [[0,0,0]] (3dfvector)

anisotropic coefficient rate in pixels, nonpositive values will be overwritten by the 'rate' value..

debug = 0 (bool)

enable additional debuging output.

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

kernel = [bspline:d=3] (factory)

transformation spline kernel. For supported plug-ins see PLUGINS:1d/splinekernel

penalty = (factory)

transformation penalty energy term. For supported plug-ins see PLUGINS:3dtransform/splinepenalty

rate = 10 (float)

isotropic coefficient rate in pixels. in [1, 3.40282e+38]

translate

Translation (three degrees of freedom), supported parameters are:

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

vf

This plug-in implements a transformation that defines a translation for each point of the grid defining the domain of the transformation., supported parameters are:

imgboundary = mirror (factory)

image interpolation boundary conditions. For supported plug-ins see PLUGINS:1d/splinebc

imgkernel = [bspline:d=3] (factory)

image interpolator kernel. For supported plug-ins see PLUGINS:1d/splinekernel

PLUGINS: 3dtransform/io

bbs

Binary (non-portable) serialized IO of 3D transformations

Recognized file extensions: .bbs

datapool

Virtual IO to and from the internal data pool

Recognized file extensions: .@

vista

Vista storage of 3D transformations

Recognized file extensions: .v, .v3dt

xml

XML serialized IO of 3D transformations

Recognized file extensions: .x3dt

PLUGINS: 3dtransform/splinepenalty

divcurl

divcurl penalty on the transformation, supported parameters are:

curl = 1 (float)

penalty weight on curl. in [0, 3.40282e+38]

div = 1 (float)

penalty weight on divergence. in [0, 3.40282e+38]

norm = 0 (bool)

Set to 1 if the penalty should be normalized with respect to the image size.

weight = 1 (float)

weight of penalty energy. in [0, 3.40282e+38]

PLUGINS: minimizer/singlecost

gdas

Gradient descent with automatic step size correction., supported parameters are:

ftolr = 0 (double)

Stop if the relative change of the criterion is below.. in [0, INF]

max-step = 2 (double)

Minimal absolute step size. in [1, INF]

maxiter = 200 (uint)

Stopping criterion: the maximum number of iterations. in [1, 2147483647]

min-step = 0.1 (double)

Maximal absolute step size. in [1e-10, INF]

xtola = 0.01 (double)

Stop if the inf-norm of the change applied to x is below this value.. in [0, INF]

gdsq

Gradient descent with quadratic step estimation, supported parameters are:

ftolr = 0 (double)

Stop if the relative change of the criterion is below.. in [0, INF]

gtola = 0 (double)

Stop if the inf-norm of the gradient is below this value.. in [0, INF]

maxiter = 100 (uint)

Stopping criterion: the maximum number of iterations. in [1, 2147483647]

scale = 2 (double)

Fallback fixed step size scaling. in [1, INF]

step = 0.1 (double)

Initial step size. in [0, INF]

xtola = 0 (double)

Stop if the inf-norm of x-update is below this value.. in [0, INF]

gsl

optimizer plugin based on the multimin optimizers ofthe GNU Scientific Library (GSL) https://www.gnu.org/software/gsl/, supported parameters are:

eps = 0.01 (double)

gradient based optimizers: stop when |grad| < eps, simplex: stop when simplex size < eps.. in [1e-10, 10]

iter = 100 (int)

maximum number of iterations. in [1, 2147483647]

opt = gd (dict)

Specific optimizer to be used.. Supported values are:

bfgs \(hy Broyden-Fletcher-Goldfarb-Shann

bfgs2 \(hy Broyden-Fletcher-Goldfarb-Shann (most efficient version)

cg-fr \(hy Flecher-Reeves conjugate gradient algorithm

gd \(hy Gradient descent.

simplex \(hy Simplex algorithm of Nelder and Mead

cg-pr \(hy Polak-Ribiere conjugate gradient algorithm

step = 0.001 (double)

initial step size. in [0, 10]

tol = 0.1 (double)

some tolerance parameter. in [0.001, 10]

nlopt

Minimizer algorithms using the NLOPT library, for a description of the optimizers please see 'http://ab-initio.mit.edu/wiki/index.php/NLopt_Algorithms', supported parameters are:

ftola = 0 (double)

Stopping criterion: the absolute change of the objective value is below this value. in [0, INF]

ftolr = 0 (double)

Stopping criterion: the relative change of the objective value is below this value. in [0, INF]

higher = inf (double)

Higher boundary (equal for all parameters). in [INF, INF]

local-opt = none (dict)

local minimization algorithm that may be required for the main minimization algorithm.. Supported values are:

gn-orig-direct-l \(hy Dividing Rectangles (original implementation, locally biased)

gn-direct-l-noscal \(hy Dividing Rectangles (unscaled, locally biased)

gn-isres \(hy Improved Stochastic Ranking Evolution Strategy

ld-tnewton \(hy Truncated Newton

gn-direct-l-rand \(hy Dividing Rectangles (locally biased, randomized)

ln-newuoa \(hy Derivative-free Unconstrained Optimization by Iteratively Constructed Quadratic Approximation

gn-direct-l-rand-noscale \(hy Dividing Rectangles (unscaled, locally biased, randomized)

gn-orig-direct \(hy Dividing Rectangles (original implementation)

ld-tnewton-precond \(hy Preconditioned Truncated Newton

ld-tnewton-restart \(hy Truncated Newton with steepest-descent restarting

gn-direct \(hy Dividing Rectangles

ln-neldermead \(hy Nelder-Mead simplex algorithm

ln-cobyla \(hy Constrained Optimization BY Linear Approximation

gn-crs2-lm \(hy Controlled Random Search with Local Mutation

ld-var2 \(hy Shifted Limited-Memory Variable-Metric, Rank 2

ld-var1 \(hy Shifted Limited-Memory Variable-Metric, Rank 1

ld-mma \(hy Method of Moving Asymptotes

ld-lbfgs-nocedal \(hy None

ld-lbfgs \(hy Low-storage BFGS

gn-direct-l \(hy Dividing Rectangles (locally biased)

none \(hy don't specify algorithm

ln-bobyqa \(hy Derivative-free Bound-constrained Optimization

ln-sbplx \(hy Subplex variant of Nelder-Mead

ln-newuoa-bound \(hy Derivative-free Bound-constrained Optimization by Iteratively Constructed Quadratic Approximation

ln-praxis \(hy Gradient-free Local Optimization via the Principal-Axis Method

gn-direct-noscal \(hy Dividing Rectangles (unscaled)

ld-tnewton-precond-restart \(hy Preconditioned Truncated Newton with steepest-descent restarting

lower = -inf (double)

Lower boundary (equal for all parameters). in [INF, INF]

maxiter = 100 (int)

Stopping criterion: the maximum number of iterations. in [1, 2147483647]

opt = ld-lbfgs (dict)

main minimization algorithm. Supported values are:

gn-orig-direct-l \(hy Dividing Rectangles (original implementation, locally biased)

g-mlsl-lds \(hy Multi-Level Single-Linkage (low-discrepancy-sequence, require local gradient based optimization and bounds)

gn-direct-l-noscal \(hy Dividing Rectangles (unscaled, locally biased)

gn-isres \(hy Improved Stochastic Ranking Evolution Strategy

ld-tnewton \(hy Truncated Newton

gn-direct-l-rand \(hy Dividing Rectangles (locally biased, randomized)

ln-newuoa \(hy Derivative-free Unconstrained Optimization by Iteratively Constructed Quadratic Approximation

gn-direct-l-rand-noscale \(hy Dividing Rectangles (unscaled, locally biased, randomized)

gn-orig-direct \(hy Dividing Rectangles (original implementation)

ld-tnewton-precond \(hy Preconditioned Truncated Newton

ld-tnewton-restart \(hy Truncated Newton with steepest-descent restarting

gn-direct \(hy Dividing Rectangles

auglag-eq \(hy Augmented Lagrangian algorithm with equality constraints only

ln-neldermead \(hy Nelder-Mead simplex algorithm

ln-cobyla \(hy Constrained Optimization BY Linear Approximation

gn-crs2-lm \(hy Controlled Random Search with Local Mutation

ld-var2 \(hy Shifted Limited-Memory Variable-Metric, Rank 2

ld-var1 \(hy Shifted Limited-Memory Variable-Metric, Rank 1

ld-mma \(hy Method of Moving Asymptotes

ld-lbfgs-nocedal \(hy None

g-mlsl \(hy Multi-Level Single-Linkage (require local optimization and bounds)

ld-lbfgs \(hy Low-storage BFGS

gn-direct-l \(hy Dividing Rectangles (locally biased)

ln-bobyqa \(hy Derivative-free Bound-constrained Optimization

ln-sbplx \(hy Subplex variant of Nelder-Mead

ln-newuoa-bound \(hy Derivative-free Bound-constrained Optimization by Iteratively Constructed Quadratic Approximation

auglag \(hy Augmented Lagrangian algorithm

ln-praxis \(hy Gradient-free Local Optimization via the Principal-Axis Method

gn-direct-noscal \(hy Dividing Rectangles (unscaled)

ld-tnewton-precond-restart \(hy Preconditioned Truncated Newton with steepest-descent restarting

ld-slsqp \(hy Sequential Least-Squares Quadratic Programming

step = 0 (double)

Initial step size for gradient free methods. in [0, INF]

stop = -inf (double)

Stopping criterion: function value falls below this value. in [INF, INF]

xtola = 0 (double)

Stopping criterion: the absolute change of all x-values is below this value. in [0, INF]

xtolr = 0 (double)

Stopping criterion: the relative change of all x-values is below this value. in [0, INF]

EXAMPLE

Register image test.v to image ref.v affine and write the registered image to reg.v. Use two multiresolution levels and ssd as cost function. mia-3drigidreg -i test.v -r ref.v -o reg.v -l 2 -f affine -c ssd

AUTHOR(s)

Gert Wollny

COPYRIGHT

This software is Copyright (c) 1999\(hy2013 Leipzig, Germany and Madrid, Spain. It comes with ABSOLUTELY NO WARRANTY and you may redistribute it under the terms of the GNU GENERAL PUBLIC LICENSE Version 3 (or later). For more information run the program with the option '--copyright'.